London-based Echopoint raises €3.5 million to improve diagnoses and treatment courses for heart disease patients | EU-Startups

London-based Echopoint raises €3.5 million to improve diagnoses and treatment courses for heart disease patients | EU-Startups

Coronary heart disease is a cause of death worldwide, in a large ‘grey for patients, a spinout from University College London, clinicians to London-based Echopoint raises precisely assess and dramatically reduce stent.

Heart attack is a leading cause of death worldwide and new treatment strategies are highly sought-after. Unfortunately lasting damage to the heart muscle is not uncommon following such an event. Published in Redox Biology, the pre-clinical study sheds new light on the potential of the acute therapy with ?-TOH (vitamin E) in patients presenting with heart attack, and may ultimately offer an effective low-cost treatment. "One of the most effective anti-oxidant and anti-inflammatory agents is vitamin E and its derivatives," said coronary heart disease treatment Professor Karlheinz Peter, the Baker Institute's Deputy Director, Basic and Translational Science and lead author of the study. "Our treatment regime reflects clinical conditions, where patients could receive their first application of vitamin E in the ambulance or upon their arrival in the emergency department, before reopening and stenting the blocked vessel and the following days in hospital before discharge. " Our next step is to test an already approved formulation of Vitamin E in patients admitted with a heart attack," said Professor Peter.

CAR T-cell therapy, may be viable treatment option for life-threatening condition: heart disease. In first-of-its-kind study, at Penn Medicine used modified T to remove activated fibroblasts Vitamin E found contribute to the development cardiac fibrosis -- process found in most heart disease in heart stiffness function the heart. The team found the significantly reduced cardiac fibrosis restored heart function in with heart CAR T-cell therapy disease caused high blood pressure. "The to harness patients' own to fight cancer has one the most research breakthroughs the decade," said the study's author Jonathan A.

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